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SHYFT Rare Disease Solution

Rare and Orphan diseases present significant data and analytics challenges related to patient and physician identification, recruitment, education, and patient services. SHYFT's Rare Disease Solution is the industry’s only end-to-end SaaS solution that does it all, in real-time, on a single integrated platform.

SHYFT platform product

STRATA Data Management

Smaller, multi-dimensional patient populations require a new breed of Big Data solutions. STRATA Data Management provides the control, flexibility, and scalability of retail data technologies with the granularity and expertise of boutique Rare Disease solutions.

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Rare Disease

Stop making compromises in how you interrogate and extract actionable insight from your rare disease data. STRATA gives you maximum control and analytical agility across your clinical, commercial and real world datasets.


  • Rare Disease Data Hub

    STRATA provides an end-to-end view of the patient experience for complete care coordination. Specialty and Rare disease product distribution, trade, advocacy, and other third party data is seamlessly integrated and made accessible through an intuitive visual interface.

  • Data Studio

    A best-in-class data management interface provides full operational confidence, visibility and control over all of your rare disease data. Monitor data diagnostics, manage users, and upload large data files directly into one unified data ecosystem.

  • Data Aggregation and Integration

    STRATA de-risks analytical agility with a robust data aggregation engine that applies governance, precedence, survivorship, de-duplication and record matching algorithms at the point of ingestion, in anticipation of downstream analytical needs.

  • Quality and Logistics Engine

    Automated data quality monitoring and lineage controls build operational confidence and deep vsibility into the impact your data processes have on the overall health of your data ecosystem.

Rare Disease

Maximize the insight value of your data by compiling the industry's most complete 360 degree views of your target entities across customer, affiliation, payer, product, service, patient and real world datasets.


  • Built for Rare Disease

    Traditional master data management (MDM) cannot keep up with the complexity, variety and veracity of rare disease datasets. STRATA MDM leverages the industry's most complete library of pre-built adapters, frameworks, APIs and business rules across 100s of rare disease and real world evidence data sources to fully automate and deliver the leading standard in master data management for rare diseases.

  • MedPro API Integration

    Direct integration of MedPro’s BulkID and DirectID capabilities enable real-time adjudication of customer records ensuring complete accuracy and confidence.

  • Data Studio

    A best-in-class data management interface provides full operational visibility and control over all of your organization’s data. Monitor data diagnostics, manage users, and upload large data files directly via an intuitive user interface.

  • Compliant, Flexible, and Scalable

    STRATA MDM is capable of processing terabytes of data and querying billions of records in seconds. It is hosted on SHYFT's HIPAA/PII/SOC2 compliant, audited and certified Amazon Cloud environment.

Rare Disease

Manage all of your outcomes data (EMR, claims, lab, omics, etc.) with ease, transparency, and full control - empowering you to stop making compromises in how you interrogate your data for insight.


  • Data Transformation

    Unify records under the OMOP standard common data model (CDM4 and CDM5).

  • Complete Data Aggregation

    Data logistics engine and business rule library drive fully-automated, asynchronous transfer, loading, and importing of all data streams.

  • Data Integrity

    Quality assurance engine continually runs data quality checks and flags issues.

  • Powerful Configurability

    Data engine powering analytics for new patient and physician segments, markets, and formulary wins.

LUMEN Insights

The smallest changes in market dynamics (patients, prescribers) can have the biggest impact on Rare Disease brand performance. LUMEN Insights provide real-time intelligence into key brand health indicators, allowing you to take action immediately to either course correct or capitalize on new pockets of opportunity.

Real-World Disease Insights

LUMEN Real-World Disease Insights dimensionalize clinical and commercial data with real-world patient outcomes in order to drive unprecedented insight into how your exact patient cohorts behave and responds to treatment in the real world.


  • Detailed Disease Overviews

    Develop detailed views into the disease landscape for your precise target patient cohort in minutes, not months. Build reports driven by Real-World Data that describe patient prevalence, incidence, demographic breakouts, lines of therapy, and cost of care.

  • Patient Journey Insights

    Drive informed go-to-market strategy through arresting interactive visualizations detailing treatment flow across lines of therapy, duration by line of therapy, disease progression, and patient outcomes.

  • Burden and Cost of Care Analytics

    Rapidly explore and test hypotheses about patient journey, burden on illness, and cost utilization to find pockets of patients with unmet need.

  • Collaborative Insight

    Easily export and share beautifully rendered insights with individual collaborators or cross-functional teams directly from the LUMEN interface.

Sales Insights

LUMEN Sales Insights provide your Rare Disease field teams with relevant and actionable information – specifically configured and beautifully presented so that their next step is obvious, intuitive, and effective. Spend less time planning and more time selling.


  • Seamless Data Integration

    Transform 100s of data sources into timely, accurate, and targeted intelligence. Our integrated Data and Analytics Platform ensures that – as information about your market, patients, and HCPs changes – your sales teams will be armed with the real-time knowledge to adjust, plan, and execute.

  • Tailored KPIs

    Develop, configure and report on your company's' custom KPIs, delivering them via intuitive dashboards to field, home office and brand teams in real-time.

  • Real-Time Triggers and Alerts

    React immediately to changing market, payer, prescriber, and patient dynamics based on configurable business rules and alerts build on custom territories, prescriber geographies, specialty groupings, market definitions and other custom business parameters.

  • Collaborative Insight

    Easily export and share beautifully rendered insights with individual collaborators or cross-functional teams directly from the LUMEN interface.

Launch Insights

When market dynamics shift, so should your launch strategy. LUMEN provides the agility and actionability to adjust and react to market complexities immediately. Key Performance Indicators and launch performance metrics are delivered across teams in real-time so that you don’t just meet expectations for your brand launch, you exceed them.


  • Launch Accelerator

    Identify target patient pools and their response to new products, as well as the services they need and the questions they are asking about the product.

  • Brand Monitor

    Measure brand performance comprehensively and in real time across your product portfolio. Integrated insights are enabled by brand, payer, and competitive intelligence, creating a complete picture to inform tactics and commercial strategies.

  • Commercial Insights

    Take immediate action through guided analytics providing campaign, performance, multi-channel, and functional area insights. A flexible platform integrated directly with your data provides the scalability to grow, quickly incorporate new sources of insight and translate them to actions.

  • Integrated Connectivity

    Create a native, bi-directional connections directly with your CRM (Veeva, SFDC, etc.), CLM, RWE, Claims, and Patient Systems to develop the most comprehensive, unified view into your business across all systems.

Market Access Insights

Competition, increasing costs, evidence-based medicine, and the rising influence of payers are reshaping the role of market access. LUMEN Market Access Insights creates a payer backbone that delivers insight that informs pull-through strategies and maximizes collaboration with the sales force. SHYFT’s supports sophisticated segmentation of payer types and facilitate integration with sales and marketing initiatives.


  • Payer Landscape Analytics

    Understand the impact of payer access restrictions on product performance as well as payer impact on territory and physician behavior.

  • Payer Segmentation

    Reveal the top opportunities for your brand through a unified view of the buying process based on product preference, access and use by line, switching, persistency, and awareness. Sharp insight into local treatment preferences gives you unprecedented insight at the regional level.

  • Account Manager Insights

    Guided analytics help inform business planning for new products, including payer level analytics such as tier status, co-pay, and reversal rates.

QUANTUM Real-World Evidence

True rapid-cycle analytics powered by your Real-World Data (RWD) allow you to generate submission-ready studies in hours, not weeks.

RWE Analytics & Observational Research

Transform outcomes data into insight in a fraction of the time of traditional analytics solutions, enabling you to drive patient value, design more successful clinical trials and respond faster to ever-changing market dynamics and safety signals.


  • Clinical Search and Cohort Generator

    Browse different clinical vocabularies’ relationships and RWE metadata and define precise patient populations with detailed inclusion and exclusion criteria – all in a simple and intuitive user interface that users across all functions and statistical skill levels can use.

  • Rapid Cycle Analysis

    Build cohorts, define variables, and run studies in a fraction of the time so that you can spend less time waiting and more time optimizing your clinical and commercial strategy. Leverage native analytic tools representing statistical best practices such as cohort attrition, measures of association, cluster analysis, regression analysis, etc.

  • Outcomes as an Advantage

    Rapidly test patient and population-level hypothesis on your precise cohort’s outcomes data to identify unmet needs, patient treatment paths, therapeutic area segments, and the relative value of pursuing additional indications. Test and validate clinical trial design protocols by easily testing unlimited sets of hypothesis around population size/trial feasibility, outcomes, and site options.

  • High-Dimension Propensity Scoring

    Arguably the gold standard in academic circles, propensity score analysis enables you to separate correlation from causality in your real world, multi-variate comparative effectiveness research. This in turn gives you unprecedented confidence in your study results.

NOVA Patient Navigator

Drive better outcomes, adherence, and access for your Rare Disease patients.

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Patient Care Coordination

Provide truly white-glove service to your patient population. Directly manage patient services, access, adherence, and persistence so that you never lose sight of a single patient.


  • Full Longitudinal Control

    Empower your patient services team to deliver an elevated patient experience with patient tracking, prescription adjudication, and adherence capabilities.

  • Centralize Patient-Centered Activity

    NOVA centralizes all patient services and engagement across support teams. Patient onboarding, case management, shipment tracking, and insurance verification enable a high-touch patient experience and valuable commercial insights.